The reigning Defensive Player of the Year has a new home, but injury is going to take a toll on his chances of repeating.
Myles Garrett won the AP NFL DPOY award unanimously in 2025, receiving all 50 first-place votes after breaking the single-season sack record with 23 sacks. That was the second DPOY win of his career, and he trails only Lawrence Taylor, J.J. Watt and Aaron Donald for the most DPOY awards in NFL history, with each of those names nabbing the award three times.
Both Watt and Donald won three in the span of four years, and while Garrett opened the year favored to do just that, a knee injury has sidelined him for now.
Let’s take a look at the odds to win the 2026 NFL Defensive Player of the Year at FanDuel Sportsbook as of Oct. 20.
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2026 NFL DPOY Odds
What To Know: Anderson is the star of a vaunted Houston defense, one that was best in the league last year. Through six games in 2026, Anderson has recorded 28 total tackles (16 solo), 7.5 sacks and 10 tackles for loss. Since Myles Garrett’s injury, he’s been the favorite in this spot. Anderson’s odds moved slightly to +170 from +120 over the last week.
Houston’s Will Anderson is the favorite to win NFL DPOY after six weeks. (Getty Images)
What To Know: Fred Warner has 58 total tackles and 27 solo in 2026. His most impressive game so far was in the 49ers’ Week 3 win over Arizona. In that game, he had 17 total tackles and seven solo. Warner has been named to the Pro Bowl four times in his career.
What To Know: On the season, Turner has 14 total tackles and 10 solo. In Week 2 in the Vikings’ win over the Bears, he had three solo tackles (five total) and two sacks. He was the 17th pick in the 2024 NFL draft. Over the last week, his odds moved slightly to +1000 from +1200.
What To Know: So far this season, Greg Rosseau has tallied 21 total tackles (14 solo), eight tackles for loss, six sacks and has forced three fumbles. In the Bills’ Week 4, 29-26 loss to New England, he had two solo tackles and assisted on two others. While the Bills got a thrilling Week 5 overtime win over the Rams, Rousseau had a quiet game with one assisted tackle. Rousseau had another relatively quiet performance in Week 6 with one assist on a tackle.
What To Know: With 15 total tackles and nine solo, the Broncos’ linebacker is making his way up the board. In Denver’s Week 6 overtime win over Seattle, Bonitto tallied four total tackles, two assists and assisted on a sack. So far, that’s been one of his best performances this season.
